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一名糖尿病患者的败血梭状芽孢杆菌菌血症(作者译)

[Clostridium septicum bacteremia in a diabetic patient (author's transl)].

作者信息

Asencio Marchante R, Marín Casanova P, García Martos P

出版信息

Med Clin (Barc). 1981 Jan 10;76(1):23-5.

PMID:7218925
Abstract

This report concerns the clinical and bacteriological study of a female diabetic who presented with a febrile illness of sudden onset and acute toxemia. Physical examination at admission was unrewarding. A few hours after admission lesions characteristic of gas gangrene appeared in the right upper limb without prior trauma, and a clostridial infection was suspected. Bacteriological studies of the exudate and of the patient's blood led to the isolation of Clostridium septicum, thus confirming the clinical suspicion. The disease had a precipitous course and the patient died 12 hours after admission in spite of the administration of high doses of intravenous penicillin. While waiting for bacteriological data, early antibiotic treatment appears to be indicated in any diabetic patient with an acute toxic syndrome and absence of localized infection.

摘要

本报告涉及一名女性糖尿病患者的临床及细菌学研究,该患者突发发热性疾病并伴有急性毒血症。入院时体格检查未发现异常。入院数小时后,右上肢体出现了气性坏疽特征性的皮损,此前并无外伤史,怀疑发生了梭菌感染。对渗出液及患者血液进行细菌学研究后,分离出了败血梭菌,从而证实了临床怀疑。病情发展迅速,尽管给予了大剂量静脉注射青霉素治疗,患者仍在入院12小时后死亡。在等待细菌学检查结果期间,对于任何患有急性中毒综合征且无局部感染的糖尿病患者,似乎都应尽早进行抗生素治疗。

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