Digranes A, Bjorvatn B
NIPH Ann. 1980 Dec;3(2):141-7.
In a multicentre study the in vitro activity of cefamandole against 3312 bacterial isolates was compared to the antibacterial activity of cephalothin, ampicillin, oxacillin, doxycycline and tobramycin. Cefamandole and tobramycin showed the highest activity against the Enterobacteriaceae isolates, whereas the Staphylococcus aureus isolates were slightly less sensitive to cefamandole than to cephalothin and oxacillin. There was no significant difference between the activity of cephalothin and cefamandole against the isolates of Haemophilus influenzae and enterococci.
在一项多中心研究中，将头孢孟多对3312株细菌分离株的体外活性与头孢噻吩、氨苄西林、苯唑西林、多西环素和妥布霉素的抗菌活性进行了比较。头孢孟多和妥布霉素对肠杆菌科分离株显示出最高活性，而金黄色葡萄球菌分离株对头孢孟多的敏感性略低于对头孢噻吩和苯唑西林的敏感性。头孢噻吩和头孢孟多对流感嗜血杆菌和肠球菌分离株的活性没有显著差异。
