Berney J L, Hahnloser P
Schweiz Med Wochenschr. 1981 Feb 7;111(6):186-90.
Of 209 unselected patients treated for bronchial carcinoma between 1976 and 1980, only 67 underwent surgery: 34 lobectomy (1 death), 19 pneumonectomy (5 deaths) and 14 exploratory thoracotomy without fatal outcome. Average survival time in lobectomy patients who died during the control period was 10 months and in those still alive 19.8 months. The corresponding figures for pneumonectomy patients were 3.9 and 17 months. Out of 142 patients considered unfit for surgery, 125 died. In the group who did not undergo radiotherapy, average survival time was 2.9 to 6.8 months depending on the histologic cell type of the carcinoma. In patients undergoing irradiation the corresponding figures were 4.7 and 7.0 months. In conclusion, radiotherapy was only of limited value in non-operated patients. Diagnosis of bronchial carcinoma is still established far too late, and therefore surgery in an unselected patient group was performed only in 32%. Lobectomy, if practicable, should be advocated as treatment of choice, whereas pneumonectomy, especially of the right side, involves marked operative mortality, provides results scarcely better than conservative treatment, and is recommended only in selected cases.
在1976年至1980年间接受支气管癌治疗的209例未经挑选的患者中,只有67例接受了手术:34例行肺叶切除术(1例死亡),19例行全肺切除术(5例死亡),14例行 exploratory thoracotomy(未提及该词准确释义,暂保留英文)且无致命后果。在对照期内死亡的肺叶切除术患者的平均生存时间为10个月,仍存活患者的平均生存时间为19.8个月。全肺切除术患者的相应数字分别为3.9个月和17个月。在142例被认为不适合手术的患者中,125例死亡。在未接受放疗的患者组中,根据癌组织学细胞类型,平均生存时间为2.9至6.8个月。接受放疗的患者的相应数字为4.7个月和7.0个月。总之,放疗对未手术患者的价值有限。支气管癌的诊断仍然建立得太晚,因此在未经挑选的患者组中只有32%进行了手术。如果可行,应提倡将肺叶切除术作为首选治疗方法,而全肺切除术,尤其是右侧全肺切除术,手术死亡率明显较高,效果 scarcely better than conservative treatment(未准确理解该短语,暂保留英文),仅在特定病例中推荐使用。