Geroulanos S, Weber A, Metzger U, Favre E, Senning A
Helv Chir Acta. 1977 Oct;44(4):535-40.
457 patients with a bronchial carcinoma of the years 1947--1962 are compared with 126 patients of the years 1969--1970 and set up in comparison to the whole clinical material of the years 1960--1975. In the period between 1969 and 1970 radical resections were performed in 20% more patients than in the first period (1947--1962). Older patients were in the last period (1970--1974) more frequent. 8% of all patients in which lobectomy was performed and 5.5% of the patients in which pneumonectomy was performed were older than 70 years of age. Overall mortality has remained unchanged for exploratory thoracotomy (19%), palliative resection (17.5%) and "radical" resection (14%). For simple pneumonectomy the overall mortality went down from 19.2% (1960--1964) to 9.6% (1970-1974) and for simple lobectomy from 14.4% to 3.8%. The five-year survival rate after radical resections was 8% (first period 0%) and after simple resections 26% (26.2%). Patients with stage I epidermoid carcinoma had a five-year survival rate of 46%. Those with stage II (spread to ipsilateral hilar nodes) a five-year survival rate of 14.3% Patients with palliative resections and exploratory thoracotomy died within 16 months.
将1947年至1962年期间的457例支气管癌患者与1969年至1970年期间的126例患者进行比较，并与1960年至1975年的全部临床资料进行对照。在1969年至1970年期间，接受根治性切除术的患者比第一阶段（1947年至1962年）多20%。老年患者在最后阶段（1970年至1974年）更为常见。在接受肺叶切除术的所有患者中，8%以及接受全肺切除术的患者中5.5%的年龄超过70岁。探查性开胸手术（19%）、姑息性切除术（17.5%）和“根治性”切除术（14%）的总体死亡率保持不变。单纯全肺切除术的总体死亡率从19.2%（1960年至1964年）降至9.6%（1970年至1974年），单纯肺叶切除术的总体死亡率从14.4%降至3.8%。根治性切除术后的五年生存率为8%（第一阶段为0%），单纯切除术后为26%（26.2%）。I期表皮样癌患者的五年生存率为46%。II期（扩散至同侧肺门淋巴结）患者的五年生存率为14.3%。接受姑息性切除术和探查性开胸手术的患者在16个月内死亡。
