Narayanan C H, Narayanan Y
J Embryol Exp Morphol. 1978 Oct;47:137-48.
The development of the ciliary ganglion with reference to the site and cells of origin have been investigated by the method of quail-to-chick transplantation of embryonic fore-, mid-and hindbrain regions, and by the method of transplantation of cranial neural crest from specific brain levels. In chimaerical embryos, quail cells originating from the graft end up in the ciliary ganglion, only when the graft is from the midbrain level of quail embryo donors. In fore- and midbrain grafts the ciliary ganglia of chimaerical embryos are composed of chick cells only. The results indicate that the mesencephalon is the principal site for the precursor cells of the ciliary ganglia and clearly rules out any contribution to the ganglia from either the forebrain or hindbrain levels. In interspecific transplantation of cranial neural crest, quail cells originating from the graft are observed consistently in the ciliary ganglion of the operated side when the grafted neural crest material is derived from the mesencephalon of quail embryo donors. On the basis of the evidence provided, it is concluded that mesencephalon is the principal site and the cranial neural crest of this level the source from which the precursor neurons of the ciliary ganglia are derived.
通过鹌鹑胚胎前脑、中脑和后脑区域向鸡胚胎移植的方法，以及从特定脑水平移植颅神经嵴的方法，研究了睫状神经节的发育及其起源部位和细胞。在嵌合体胚胎中，只有当移植组织取自鹌鹑胚胎供体的中脑水平时，源自移植组织的鹌鹑细胞才会最终进入睫状神经节。在前脑和中脑移植中，嵌合体胚胎的睫状神经节仅由鸡细胞组成。结果表明，中脑是睫状神经节前体细胞的主要来源部位，明确排除了前脑或后脑水平对神经节的任何贡献。在颅神经嵴的种间移植中，当移植的神经嵴组织取自鹌鹑胚胎供体的中脑时，在手术侧的睫状神经节中始终能观察到源自移植组织的鹌鹑细胞。根据所提供的证据，得出结论：中脑是主要部位，该水平的颅神经嵴是睫状神经节前体神经元的来源。
