溶组织内阿米巴的表面特性：致病菌株中人类红细胞吞噬率增加。
Surface properties of Entamoeba: increased rates of human erythrocyte phagocytosis in pathogenic strains.
作者信息
Trissl D, Martínez-Palomo A, de la Torre M, de la Hoz R, Pérez de Suárez E
出版信息
J Exp Med. 1978 Nov 1;148(5):1137-43. doi: 10.1084/jem.148.5.1137.
Abstract
The assertion that ingestion of human erythrocytes is restricted to invasive strains of Entamoeba histolytica has not been evaluated previously by comparative studies. In this report we describe the in vitro ingestion of human erythrocytes by pathogenic and nonpathogenic Entamoeba. Microscopic evaluation of erythrophagocytosis by eight different Entamoeba grown in culture revealed that strains of E. histolytica isolated from cases of human dysentery show a much higher rate of erythrocyte ingestion than nonpathogenic strains. However, all strains are able to phagocytize erythrocytes. The extremely high rate of phagocytic activity shown by pathogenic E. histolytica could be one of the properties related to the pathogenicity of this parasitic protozoan.
摘要
关于摄入人体红细胞仅限于侵袭性溶组织内阿米巴菌株这一论断，此前尚未通过比较研究进行评估。在本报告中，我们描述了致病性和非致病性阿米巴对人体红细胞的体外摄取情况。对在培养中生长的八种不同阿米巴进行红细胞吞噬作用的显微镜评估显示，从人类痢疾病例中分离出的溶组织内阿米巴菌株比非致病性菌株表现出更高的红细胞摄取率。然而，所有菌株都能够吞噬红细胞。致病性溶组织内阿米巴表现出的极高吞噬活性可能是与这种寄生原生动物致病性相关的特性之一。
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