Susani M
Wien Klin Wochenschr. 1981 Jan 9;93(1):24-8.
A case is reported of granulomatous placentitis due to Toxoplasma infection, which led, like two similar cases reported in the literature to abortion within the first half of pregnancy. The author tries to interpret the pathogenesis of this rare type of reaction. In view of the early onset of infection a complete immune response of the fetus in this state of development appears unlikely. The question arises whether maternal immuno-competent cells might be responsible for this mature immune reaction, which took the form of granulomatous inflammation of the placenta. A prerequisite for this type of reaction is considered to be prolonged retention of vital placental tissue in the uterus in intra-uterine death of the fetus or complete abortion.
本文报道了一例因弓形虫感染引起的肉芽肿性胎盘炎病例，与文献中报道的另外两例相似病例一样，该病例导致妊娠前半期流产。作者试图解释这种罕见反应类型的发病机制。鉴于感染发生较早，处于这种发育状态的胎儿似乎不太可能产生完全的免疫反应。问题在于，母体免疫活性细胞是否可能是这种成熟免疫反应的原因，这种反应表现为胎盘的肉芽肿性炎症。这种反应类型的一个先决条件被认为是胎儿宫内死亡或完全流产时，存活的胎盘组织在子宫内长期留存。
