Kralios F A, Millar C K
Am J Physiol. 1981 Apr;240(4):H590-6. doi: 10.1152/ajpheart.1981.240.4.H590.
The functional distribution of the cardiac sympathetic nerves to the atria and their arrhythmiogenic effects were determined in 16 open-chest pentobarbital-anesthetized dogs. Shortening of refractory periods at four right and two left atrial sites during stimulation of the nerves was taken as a criterion of their distribution. Stimulation of right stellate ganglion, craniovagal, and right stellate cardiac nerves produced localized shortening on the right atrium, particularly at the sinus node area, and invariably induced sinus tachycardia. The recurrent cardiac nerve produced little shortening at all sites and less arrhythmiogenic effect. The left stellate ganglion and ventrolateral cardiac nerve affected only left atrial sites and induced atrioventricular junctional rhythm. The ventromedial cardiac nerve affected all sites and had no consistent arrhythmiogenic effect. The innominate nerve had no substantial effect. We concluded that the functional distribution of the cardiac sympathetic nerves is localized, and that rate, rhythm, and refractory period changes induced by stimulation of these nerves are characteristic of the area of distribution.
在16只戊巴比妥钠麻醉的开胸犬中，测定了心脏交感神经向心房的功能分布及其致心律失常作用。在神经刺激期间，将四个右心房和两个左心房部位的不应期缩短作为其分布的标准。刺激右星状神经节、颅迷走神经和右星状心神经会导致右心房局部缩短，尤其是在窦房结区域，并总是诱发窦性心动过速。返行心神经在所有部位产生的缩短很少，致心律失常作用也较小。左星状神经节和心外侧神经仅影响左心房部位，并诱发房室交界性心律。心内侧神经影响所有部位，且没有一致的致心律失常作用。无名神经没有实质性影响。我们得出结论，心脏交感神经的功能分布是局部性的，并且刺激这些神经所引起的心率、心律和不应期变化是分布区域的特征。
