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低剂量激光对小鼠视网膜功能活动的影响。

The effect of low dose laser on the functional activities of the mice retina.

作者信息

Poon A M, Yew D T

出版信息

Anat Anz. 1980;148(3):236-44.

PMID:7224182
Abstract

The amount of uridine uptake of the retina, the phagosome number and the acid phosphatase activity of the pigment epithelial cells after low dose laser treatment were studied. It was found that uridine uptake in the treated retina increased as early as one hour after laser treatment and then gradually returned to normal. The phagosome number showed a decrease 15 minutes after treatment followed by an increase. Finally it returned to normal 160 hours post-treatment. Higher acid phosphatase activity was found in the laser treated eye one hour and 16 hours after treatment and becoming normal again after 40 hours. It was postulated that the synthetic rate of the visual cells was stimulated by laser treatment. The increase in the shedding of the rod outer segments occurred simultaneously with the increase of phagocytic activity of the pigment epithelial cells. The increase of acid phosphatase activity of the pigment epithelial cells was a consequence of the increased phagocytic activity.

摘要

研究了低剂量激光治疗后视网膜的尿苷摄取量、色素上皮细胞的吞噬体数量和酸性磷酸酶活性。结果发现,激光治疗后1小时,治疗后的视网膜尿苷摄取量即开始增加,随后逐渐恢复正常。吞噬体数量在治疗后15分钟减少,随后增加。最终在治疗后160小时恢复正常。治疗后1小时和16小时,激光治疗眼的酸性磷酸酶活性较高,40小时后恢复正常。据推测,激光治疗刺激了视觉细胞的合成速率。视杆细胞外段脱落增加与色素上皮细胞吞噬活性增加同时发生。色素上皮细胞酸性磷酸酶活性增加是吞噬活性增加的结果。

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