正常和低动脉血氧分压条件下，麻醉猫窦神经中化学感受器传入纤维放电频率的呼吸振荡。
Respiratory oscillations in discharge frequency of chemoreceptor afferents in sinus nerve and anaesthetized cats at normal and low arterial oxygen tensions.
作者信息
Band D M, Wolff C B
出版信息
J Physiol. 1978 Sep;282:1-6. doi: 10.1113/jphysiol.1978.sp012443.
Abstract
- The discharge of chemoreceptor afferents in preparations of the sinus nerve in spontaneously breathing anaesthetized cats has been subjected to an averaging procedure in records obtained when the animals breathed (a) air and (b) a hypoxic gas mixture. 2. The mean discharge frequency was higher in hypoxia than at normal oxygen tension. 3. Oscillations in chemoreceptor discharge frequency with the same period as respiration were obtained by the averaging procedure both at normal arterial oxygen tensions and in hypoxia, but there was no significant increase in oscillation amplitude with hypoxia. 4. The carotid body response to arterial PCO2 oscillations does not therefore appear to be amplified by hypoxia. This finding is discussed in relation to the reported dependence upon hypoxia of the ventilatory effects of tube breathing in man.
摘要
- 在自主呼吸的麻醉猫的窦神经制备物中，当动物呼吸（a）空气和（b）低氧气体混合物时，对化学感受器传入神经的放电进行了平均处理。2. 低氧时的平均放电频率高于正常氧张力时。3. 通过平均处理，在正常动脉氧张力和低氧状态下均获得了与呼吸周期相同的化学感受器放电频率振荡，但低氧时振荡幅度无显著增加。4. 因此，颈动脉体对动脉血二氧化碳振荡的反应似乎不会因低氧而增强。结合人类中报道的管呼吸通气效应依赖于低氧这一情况对该发现进行了讨论。
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