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通过管子呼吸对猫的反射性呼吸影响。

The reflex respiratory effects on cats of breathing through a tube.

作者信息

Marsh J, Nye P C

出版信息

J Physiol. 1982 Apr;325:353-62. doi: 10.1113/jphysiol.1982.sp014154.

Abstract
  1. In anaesthetized cats, breathing air through an external dead space (a tube, 20-40 ml.) stimulated ventilation in excess of that expected from the end-tidal gases. 2. The stimulatory effect remained after bilateral vagotomy. 3. The stimulatory effect was reduced or abolished after bilateral section of the carotid sinus nerves. 4. The stimulatory effect was abolished by bilateral section of both the vagi and the sinus nerves. 5. Recording from chemoreceptor afferents in the sinus nerve showed that, although the tube increased mean discharge frequency, this increase was insufficient to account for the stimulation of ventilation observed. 6. Some feature of chemoreceptor discharge other than its mean level, possibly related to its wave form, may explain the effect.
摘要
  1. 在麻醉猫中,通过外部无效腔(一根20 - 40毫升的管子)呼吸空气会刺激通气,其通气量超过根据终末潮气气体所预期的量。2. 双侧迷走神经切断术后,刺激作用仍然存在。3. 双侧切断颈动脉窦神经后,刺激作用减弱或消失。4. 双侧切断迷走神经和窦神经后,刺激作用消失。5. 对窦神经中的化学感受器传入纤维进行记录表明,尽管管子增加了平均放电频率,但这种增加不足以解释所观察到的通气刺激。6. 化学感受器放电的某些特征而非其平均水平,可能与其波形有关,或许可以解释这种效应。

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本文引用的文献

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Quantitation of chemoreceptor activity: interrelation of hypoxia and hypercapnia.
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Chemoreceptor effects in the respiratory cycle.
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Carotid chemoreceptor response to intermittent or sustained stimulation in the cat.
Respir Physiol. 1969 Apr;6(3):395-402. doi: 10.1016/0034-5687(69)90037-1.
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Respir Physiol. 1968 Jan;4(1):91-100. doi: 10.1016/0034-5687(68)90010-8.
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The effect on respiration of abrupt changes in carotid artery pH and PCO2 in the cat.
J Physiol. 1970 Dec;211(2):479-94. doi: 10.1113/jphysiol.1970.sp009288.

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