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人结肠腺癌(LOVO)异种移植系统中的血清癌胚抗原水平。

Serum CEA levels in a human colonic adenocarcinoma (LOVO) xenograft system.

作者信息

Stragand J J, Yang L Y, Drewinko B

出版信息

Cancer Lett. 1980 Jul;10(1):45-50. doi: 10.1016/0304-3835(80)90064-6.

DOI:10.1016/0304-3835(80)90064-6
PMID:7226129
Abstract

The relationship between tumor size and circulating CEA titers was examined for a human colonic adenocarcinoma xenografted in Balb/C athymic mice. Xenograft material was derived from line LoVo, which produces moderate amounts of CEA, both in vitro and in vivo. No correlation was found between tumor size and serum CEA levels.

摘要

研究了移植于Balb/C无胸腺小鼠体内的人结肠腺癌异种移植物中肿瘤大小与循环癌胚抗原(CEA)滴度之间的关系。异种移植材料来源于LoVo细胞系,该细胞系在体外和体内均产生中等量的CEA。未发现肿瘤大小与血清CEA水平之间存在相关性。

相似文献

1
Serum CEA levels in a human colonic adenocarcinoma (LOVO) xenograft system.人结肠腺癌(LOVO)异种移植系统中的血清癌胚抗原水平。
Cancer Lett. 1980 Jul;10(1):45-50. doi: 10.1016/0304-3835(80)90064-6.
2
Tumor volume correlated serum CEA levels in nude mice after primary xenotransplantation of human colorectal carcinoma.人结直肠癌原位异种移植后裸鼠的肿瘤体积与血清癌胚抗原水平相关。
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Growth potential of human colorectal carcinomas in nude mice: association with the preoperative serum concentration of carcinoembryonic antigen in patients.人结肠直肠癌在裸鼠体内的生长潜能:与患者术前血清癌胚抗原浓度的关联
Cancer Res. 1988 Mar 15;48(6):1689-92.
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Carcinoembryonic antigen production, secretion, and kinetics in BALB/c mice and a nude mouse-human tumor model.癌胚抗原在BALB/c小鼠及裸鼠-人肿瘤模型中的产生、分泌及动力学
Cancer Res. 1984 Dec;44(12 Pt 1):5475-81.
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Relationship of serum CEA levels to tumour size and CEA content in nude mice bearing colonic-tumour xenografts.携带结肠肿瘤异种移植瘤的裸鼠血清癌胚抗原(CEA)水平与肿瘤大小及CEA含量的关系
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Somatostatin inhibits both in-vitro and in-vivo carcinoembryonic antigen secretion by human colon cancer.生长抑素可抑制人结肠癌在体外和体内分泌癌胚抗原。
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Ability of CEA blood levels to reflect tumour burden: a study in a human xenograft model.癌胚抗原(CEA)血水平反映肿瘤负荷的能力:一项人类异种移植模型研究
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Growth of human colonic adenocarcinoma and development of serum CEA in in athymic mice. I: Strict correlation of tumour size and mass with serum CEA concentration during logarithmic growth.人结肠腺癌在无胸腺小鼠体内的生长及血清癌胚抗原的产生。I:对数生长期肿瘤大小和质量与血清癌胚抗原浓度的严格相关性。
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Chemotherapy with daunorubicin-anti-CEA conjugates in human colon adenocarcinoma grafted in nude mice.用柔红霉素-抗癌胚抗原偶联物对移植于裸鼠的人结肠腺癌进行化疗。
Semin Oncol. 1984 Dec;11(4 Suppl 3):56-8.

引用本文的文献

1
Cytotoxicity of lymphocytes activated by superantigen toxic-shock-syndrome toxin-1 against colorectal cancer LoVo cells.超抗原性中毒性休克综合征毒素-1 激活的淋巴细胞对结直肠癌细胞 LoVo 的细胞毒性。
Mol Cell Biochem. 2013 Apr;376(1-2):1-9. doi: 10.1007/s11010-013-1561-6. Epub 2013 Jan 24.
2
Relationship of serum CEA levels to tumour size and CEA content in nude mice bearing colonic-tumour xenografts.携带结肠肿瘤异种移植瘤的裸鼠血清癌胚抗原(CEA)水平与肿瘤大小及CEA含量的关系
Br J Cancer. 1981 Sep;44(3):381-7. doi: 10.1038/bjc.1981.195.
3
Growth of human colonic adenocarcinoma and development of serum CEA in in athymic mice. I: Strict correlation of tumour size and mass with serum CEA concentration during logarithmic growth.
人结肠腺癌在无胸腺小鼠体内的生长及血清癌胚抗原的产生。I:对数生长期肿瘤大小和质量与血清癌胚抗原浓度的严格相关性。
Br J Cancer. 1982 Dec;46(6):841-7. doi: 10.1038/bjc.1982.293.
4
Ability of CEA blood levels to reflect tumour burden: a study in a human xenograft model.癌胚抗原(CEA)血水平反映肿瘤负荷的能力:一项人类异种移植模型研究
Br J Cancer. 1982 Aug;46(2):220-7. doi: 10.1038/bjc.1982.187.
5
Carcinoembryonic antigen (CEA) in human colorectal cancers growing subcutaneously in nude mice.裸鼠皮下生长的人结直肠癌中的癌胚抗原(CEA)
J Cancer Res Clin Oncol. 1983;105(3):238-42. doi: 10.1007/BF00395751.
6
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Jpn J Cancer Res. 1990 Jan;81(1):58-62. doi: 10.1111/j.1349-7006.1990.tb02507.x.