Jones J T, Andrews S J
J Reprod Fertil. 1978 Nov;54(2):357-62. doi: 10.1530/jrf.0.0540357.
The activity of G6PD was examined by spectrophotometric and electrophoretic assays in cell fractions from the testes of mice at different ages (5-62 days). (1) The G6PD activity of the cells of the seminiferous tubule was as high or higher than that of the interstitial tissue. (2) The high G6PD activity of the testis of the immature mouse was mainly due to a high specific activity of the Sertoli cells which declined with age. (3) The G6PD activity was more easily lost during culture from the germinal cells than from the interstitial or Sertoli cells. (4) All the cell types of the testis contained G6PD and hexose-6-phosphate dehydrogenase. The functional significance of the high G6PD activity in the Sertoli cells of immature mice is not at present understood.
通过分光光度法和电泳分析，检测了不同年龄（5 - 62天）小鼠睾丸细胞组分中的葡萄糖-6-磷酸脱氢酶（G6PD）活性。（1）生精小管细胞的G6PD活性与间质组织的活性相当或更高。（2）未成熟小鼠睾丸的高G6PD活性主要归因于支持细胞的高比活性，该活性随年龄下降。（3）在培养过程中，生殖细胞的G6PD活性比间质细胞或支持细胞更容易丧失。（4）睾丸的所有细胞类型都含有G6PD和6-磷酸己糖脱氢酶。目前尚不清楚未成熟小鼠支持细胞中高G6PD活性的功能意义。
