儿科患者抗生素治疗的控制。一、医院抗生素处方收集与分析计算机系统。

Control of antibiotic therapy in pediatric patients. I. A computer system to collect and analyze antibiotic prescriptions in hospitals.

作者信息

Principi N, Sher D, Moresco R C, Marchisio P, Boccazzi A, Viola G, Sereni F

出版信息

Dev Pharmacol Ther. 1981;2(3):145-55.

Abstract

A computer system to record and analyze antibiotic prescriptions in hospitalized children is described. This system is especially organized in order to obtain simultaneously a quantitative evaluation of antibiotic use and a qualitative analysis of the process by which the physician makes his decision for therapy. The practical employment of this program has been demonstrated by analyzing 765 prescriptions given in nine different pediatric hospital wards. Many errors of prescription have been demonstrated: antibiotic therapy was based on the clinical impression alone in 31.5% of the prescriptions, antibiotic choice was rational in 20.1% and the posology prescribed complied with the usually applied schemes in 22.4%. Finally, the physician's attitude regarding laboratory monitoring of side effects was adequate in 52.8% before treatment and 33.4% during antibiotic treatment.

摘要

本文描述了一个用于记录和分析住院儿童抗生素处方的计算机系统。该系统经过专门设计，以便同时对抗生素使用情况进行定量评估，并对医生做出治疗决策的过程进行定性分析。通过分析九个不同儿科病房开出的765张处方，证明了该程序的实际应用情况。结果显示出许多处方错误：31.5%的处方中抗生素治疗仅基于临床印象，20.1%的抗生素选择合理，22.4%的处方剂量符合常用方案。最后，在治疗前，医生对副作用实验室监测的态度有52.8%是恰当的，在抗生素治疗期间这一比例为33.4%。