Schmidt K D, Abiodun P, Tolckmitt W
Eur J Pediatr. 1981 May;136(2):193-7. doi: 10.1007/BF00441923.
The viscosity of gastric juice and the concentrations of sodium, potassium, calcium, magnesium and chloride ions were measured before and after stimulation with pentagastrin in 10 children with cystic fibrosis and compared to those in 10 healthy children of corresponding ages. The viscosity values followed the same patterns as those for the sodium and calcium ion concentrations and were higher in the cystic fibrosis group. The electrolyte concentrations in the basal and different post-stimulation fractions of the gastric juice were higher in the cystic fibrosis group. Significant differences between both groups could only be found in the electrolyte concentrations. The total secretion of each of the electrolytes was the same in both groups because along with the increased electrolyte concentration in the cystic fibrosis group there was a reduced volume of gastric juice. The dependence of viscosity on the individual electrolyte concentration is discussed. The differences in the viscosity and the electrolyte concentrations in gastric juice from the cystic fibrosis children seems to be due to changes in the process of gastric secretion and not due to the influence of swallowed saliva.
对10名囊性纤维化患儿在使用五肽胃泌素刺激前后的胃液黏度以及钠、钾、钙、镁和氯离子浓度进行了测量，并与10名相应年龄的健康儿童进行比较。黏度值与钠和钙离子浓度的变化模式相同，且在囊性纤维化组中更高。囊性纤维化组胃液基础分泌液和不同刺激后分泌液中的电解质浓度更高。两组之间仅在电解质浓度上存在显著差异。两组中每种电解质的总分泌量相同，因为在囊性纤维化组中，随着电解质浓度的增加，胃液分泌量减少。讨论了黏度与个体电解质浓度的相关性。囊性纤维化患儿胃液的黏度和电解质浓度差异似乎是由于胃分泌过程的改变，而非吞咽唾液的影响。
