Gjesing B
West Afr J Pharmacol Drug Res. 1975 Jun;2(1):10-6.
The output of acid, chloride, sodium and potassium in gastric washings from the Vervet monkey have been measured under basal conditions and while stimulating the secretion with two doses of pentagastrin (one dose submaximal, the other dose supramaximal). The output during washings with different weak electrolyte solutions (5 mEq/1 NaC1, KCl, or HCl or 0.36 M Glycine) are compared. The results show that the composition of the secretion was independent of the composition of the rinsing fluid in the stomach except that glycine stimulated acid and potassium secretion when the monkey was not stimulated by pentagastrin. These observations and the composition of the gastric secretion of the Vervet monkey are discussed in the light of the "two-component" and "exchange" models of gastric secretion, and which compared with the gastric juice obtained from humans under similar conditions.
在基础条件下以及用两种剂量的五肽胃泌素(一种次最大剂量,另一种超最大剂量)刺激分泌时,已对绿猴胃灌洗物中的酸、氯、钠和钾的排出量进行了测量。比较了用不同弱电解质溶液(5 mEq/1氯化钠、氯化钾、盐酸或0.36 M甘氨酸)灌洗期间的排出量。结果表明,除了在猴子未受到五肽胃泌素刺激时甘氨酸刺激酸和钾分泌外,分泌成分与胃中冲洗液的成分无关。根据胃分泌的“双组分”和“交换”模型对这些观察结果以及绿猴胃分泌的成分进行了讨论,并与在类似条件下从人类获得的胃液进行了比较。