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[具有潜在抗肿瘤活性的 2-取代噻唑衍生物]

[2-Substituted thiazole derivatives with possible antitumor activity].

作者信息

Monforte P, Grasso S, Chimirri A, Fenech G

出版信息

Farmaco Sci. 1981 Feb;36(2):109-15.

PMID:7227500
Abstract

Some di-N-(20-aminothiazolyl)derivatives were synthesized and then cyclyzed to give the thiazolidin-4-ones (II) and (III). All compounds were tested for their activity against the leukemic P 388 tumor system in mice.

摘要

合成了一些二 - N -（20 - 氨基噻唑基）衍生物，然后将其环化得到噻唑烷 - 4 - 酮（II）和（III）。对所有化合物进行了针对小鼠白血病P 388肿瘤系统的活性测试。

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