补体在病毒感染中的作用：末端补体成分（C5至C9）参与小鼠从辛德毕斯病毒感染中恢复。
Role of complement in viral infections: participation of terminal complement components (C5 to C9) in recovery of mice from Sindbis virus infection.
作者信息
Hirsch R L, Griffin D E, Winkelstein J A
出版信息
Infect Immun. 1980 Dec;30(3):899-901. doi: 10.1128/iai.30.3.899-901.1980.
Abstract
the pathogenesis of Sindbis virus infection was studied in congenic mice with normal levels of the fifth component of complement (C5) and in mice deficient in C5. Mice deficient in C5 had a higher mortality rate than mice with normal levels of C5 as well as impaired clearance of virus from their brain and feet.
摘要
在具有正常补体第五成分（C5）水平的同基因小鼠和缺乏C5的小鼠中研究了辛德毕斯病毒感染的发病机制。缺乏C5的小鼠比具有正常C5水平的小鼠死亡率更高，并且其从大脑和足部清除病毒的能力受损。
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Role of complement in viral infections: participation of terminal complement components (C5 to C9) in recovery of mice from Sindbis virus infection.补体在病毒感染中的作用：末端补体成分（C5至C9）参与小鼠从辛德毕斯病毒感染中恢复。
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本文引用的文献
1
The role of complement in viral infections. II. the clearance of Sindbis virus from the bloodstream and central nervous system of mice depleted of complement.补体在病毒感染中的作用。II. 从缺乏补体的小鼠血液循环和中枢神经系统中清除辛德毕斯病毒
J Infect Dis. 1980 Feb;141(2):212-7. doi: 10.1093/infdis/141.2.212.
2
Role of the immune response in age-dependent resistance of mice to encephalitis due to Sindbis virus.免疫反应在小鼠对辛德毕斯病毒所致脑炎的年龄依赖性抵抗力中的作用。
J Infect Dis. 1976 Apr;133(4):456-64. doi: 10.1093/infdis/133.4.456.
3
4
The effect of complement depletion on the course of Sindbis virus infection in mice.补体耗竭对小鼠辛德毕斯病毒感染病程的影响。
J Immunol. 1978 Oct;121(4):1276-8.
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