Proppe D W
J Appl Physiol Respir Environ Exerc Physiol. 1981 May;50(5):974-8. doi: 10.1152/jappl.1981.50.5.974.
This study examined the influence of elevated skin temperature (Tsk) on the central thermoregulatory control of leg blood flow in five unanesthetized, chronically instrumented, resting baboons (Papio anubis and P. cynocephalus). In each experiment, mean iliac blood flow (MIBF), mean arterial blood pressure, arterial blood temperature (Tbl), and Tsk were measured, and iliac vascular conductance (IVC) was calculated. A heat exchanger was incorporated into a chronic arteriovenous femoral shunt to control Tbl. The protocol consisted of raising Tbl approximately 2.6 degrees C in thermoneutral environment (cool Tsk) an then again after Tsk had been elevated by environmental heating. A major influence of raising Tsk was the lowering of threshold Tbl at which the rise in MIBF and IVC commenced. This threshold Tbl was lowered at least 0.8 degrees C on the average. Also, over the whole range of Tbl studied (37.0-39.6 degrees C), MIBF and IVC were higher at high Tsk than at cool Tsk. Thus an elevation of Tsk significantly influences the control of skin blood flow by central thermoreceptors.
本研究检测了皮肤温度（Tsk）升高对5只未麻醉、长期植入仪器且处于静息状态的狒狒（阿拉伯狒狒和东非狒狒）腿部血流的中枢体温调节控制的影响。在每个实验中，测量了髂平均血流（MIBF）、平均动脉血压、动脉血温度（Tbl）和Tsk，并计算了髂血管传导率（IVC）。将一个热交换器并入慢性股动静脉分流装置以控制Tbl。实验方案包括在热中性环境（凉爽的Tsk）中将Tbl升高约2.6摄氏度，然后在环境加热使Tsk升高后再次升高Tbl。升高Tsk的一个主要影响是降低了MIBF和IVC开始升高时的Tbl阈值。该Tbl阈值平均降低了至少0.8摄氏度。此外，在所研究的整个Tbl范围内（37.0 - 39.6摄氏度），高Tsk时的MIBF和IVC高于凉爽Tsk时的。因此，Tsk升高显著影响中枢温度感受器对皮肤血流的控制。
