Parrish J A, Jaenicke K F
J Invest Dermatol. 1981 May;76(5):359-62. doi: 10.1111/1523-1747.ep12520022.
Using a monochromator the action spectrum for ultraviolet phototherapy of psoriasis was determined for radiation between 254 and 313 nm and compared to the action spectrum for erythema of uninvolved adjacent skin. Daily exposures of different doses of 254, 280, 290, 296, 300, 304 and 313 nm radiation were observed. Wavelengths of 254, 280, 290 nm were erythemogenic but not therapeutic even at 10 to 50 times the minimal erythema dose. At the other wavelengths studied, the 2 action spectra were similar. In general, fixed daily doses cleared at lower cumulative dose than did incrementally increased daily doses. The small number of suberythemogenic exposure doses required suggests that monochromatic radiation may have advantages over broadband sources.
使用单色仪测定了254至313纳米之间紫外线光疗银屑病的作用光谱，并与未受累相邻皮肤红斑的作用光谱进行了比较。观察了不同剂量的254、280、290、296、300、304和313纳米辐射的每日照射情况。254、280、290纳米波长具有致红斑作用，但即使是最小红斑剂量的10至50倍也没有治疗效果。在所研究的其他波长下，两种作用光谱相似。一般来说，固定的每日剂量比逐渐增加的每日剂量在更低的累积剂量时就能清除病变。所需的亚红斑照射剂量较少，这表明单色辐射可能比宽带光源具有优势。
