Estimation of decision criteria for the uric acid concentration for the early diagnosis of gestosis.

An increase of the serum uric acid concentration of pregnant women can indicate an EPH gestosis with a high risk. Above a uric acid level of 270 mumol/l (and of 315 mumol/l after the 32nd. week of pregnancy) and gestosis has become moderate. An increased risk for mother and fetus must then be assumed. This decision point is estimated by comparing three techniques: The ROC-curve-method and the determination of the maximal efficiency and of the maximal information content.