Serum lipid levels in iron deficiency anemia and effects of various treatments.

Effects of anemia on serum total cholesterol and triglyceride levels were studied in Sri Lanka. In subjects with hemoglobin (Hb) levels of less than 9.0 g/100 ml, there was a significant relationship between Hb and cholesterol levels (r = 0.53). This relationship was not seen in subjects with Hb levels equal to, or greater than, 9.0 g/100 ml. Triglyceride levels were independent of Hb levels. Total cholesterol levels were elevated following an increase in Hb levels by transfusion and iron treatment. It was suggested that the concentration of red blood cells may affect cholesterol synthesis or mobilization from tissue to plasma.