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[缺铁性贫血患者外周血红细胞脂质与心肌营养不良]

[The erythrocyte lipids of the peripheral blood and myocardial dystrophy in patients with iron-deficiency anemia].

作者信息

Paramonova I V, Kirilenko N P

出版信息

Ter Arkh. 1993;65(11):57-60.

PMID:8108801
Abstract

Lipids of peripheral blood red cells (total lipids and phospholipids, triglycerides, free fatty acids, cholesterol, cholesterol ethers, lysophospholipids, sphingomyelins, phosphatidylserins, phosphatidylethanolamines, phosphatidylcholines, cardiolipins, phosphatid acids) were assessed in correlation with wave T height on resting ECG. It is shown that iron deficiency anemia patients develop shifts in red blood cell lipid composition contributing to the onset of myocardiodystrophy. The correction of the lipid composition defects is an additional factor decreasing dystrophic processes in the myocardium.

摘要

对外周血红细胞的脂质(总脂质、磷脂、甘油三酯、游离脂肪酸、胆固醇、胆固醇醚、溶血磷脂、鞘磷脂、磷脂酰丝氨酸、磷脂酰乙醇胺、磷脂酰胆碱、心磷脂、磷脂酸)进行了评估,并与静息心电图上的T波高度进行相关性分析。结果表明,缺铁性贫血患者红细胞脂质组成发生变化,这有助于心肌营养不良的发生。纠正脂质组成缺陷是减少心肌营养不良过程的一个额外因素。

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