Lewis R R, Beasley M G, Gosling R G
J R Soc Med. 1980 Mar;73(3):172-9. doi: 10.1177/014107688007300304.
A two-stage approach is described for the detection of occlusive arterial disease at the carotid bifurcation using continuous wave Doppler-shift ultrasound with spectral analysis of backscattered signals from erythrocytes. The first stage involves analysis of Doppler-shift signals from the supraorbital and common carotid arteries. Abnormal signals from these arteries are frequently caused by the presence of atheroma at the carotid bifurcation and are used to indicate the necessity for imaging the bifurcation. This latter technique produces a physiological image of the arteries, as it depends on detecting erythrocyte velocities beneath a transducer which is guided over the surface of the neck. The investigation has advantages over arteriography in that it is noninvasive, has no attendant risk and may be repeated as often as required.In order to evaluate the accuracy of these methods the results have been compared with x-ray findings in patients undergoing carotid arteriography. In 20 comparisons there were no false positives and one false negative in which the arteriogram showed a small lesion. These results indicate that the two noninvasive methods may be used in sequence to demonstrate operable disease around the carotid junction.
本文描述了一种两阶段方法，用于使用连续波多普勒频移超声和对红细胞反向散射信号进行频谱分析来检测颈动脉分叉处的闭塞性动脉疾病。第一阶段涉及对眶上动脉和颈总动脉的多普勒频移信号进行分析。这些动脉的异常信号通常是由颈动脉分叉处的动脉粥样硬化引起的，并用于指示对分叉处进行成像的必要性。后一种技术产生动脉的生理图像，因为它依赖于检测在颈部表面引导的换能器下方的红细胞速度。该研究相对于动脉造影具有优势，因为它是非侵入性的，没有伴随风险，并且可以根据需要多次重复。为了评估这些方法的准确性，已将结果与接受颈动脉造影的患者的X射线检查结果进行了比较。在20次比较中，没有假阳性，有1例假阴性，动脉造影显示有一个小病变。这些结果表明，这两种非侵入性方法可以依次使用，以显示颈动脉交界处周围的可手术疾病。
