Judaki Arezo, Hafeziahmadi Mohamadreza, Yousefi Atefe, Havasian Mohamad Reza, Panahi Jafar, Sayehmiri Koroush, Alizadeh Sajjad
Department of Gastroenterology, Ilam University of Medical Sciences, Ilam/ Iran.
Department of Pathology, Ilam University of Medical Sciences, Ilam/ Iran.
Bioinformation. 2014 Nov 27;10(11):693-6. doi: 10.6026/97320630010693. eCollection 2014.
The intestine is the largest mucosal organ of the body and also the first line immune homeostasis. Inflammatory bowel disease or IBD is divided into ulcerative colitis and Crohn's disease. One of the problems that can occur with UC is dietary allergy to some foods. This study aimed to evaluated the dairy allergy among patients with ulcerative colitis. This study is a Case - control study, that studied 72 patients with Ulcerative Colitis, after recording history of the disease, colonoscopy and confirmed by biopsy and 72 person without history of colitis. In this study, in order to investigate of food allergy, used of the EUROMMUM kit with an international code number DP3420-1601-11E. We used chi-square and Monte Carlo method for analysis of data. Among UC patients, 30.6% mild, 52.8% moderate and 16.6% of cases were in sever stage. 9.7% of them reported a history of abdominal surgery due to disease. According to the chi-square and Monte Carlo methods, dairy allergy (including: cow milk, cow milk UHT and casein) in UC group was significant (P=0.00). This study indicated that there is significant relationship between UC and cow milk, cow milk UHT and casein. UC patients who are allergic to dairy products and the use of dairy products can increase the severity of UC.
肠道是人体最大的黏膜器官，也是免疫稳态的第一道防线。炎症性肠病（IBD）分为溃疡性结肠炎和克罗恩病。溃疡性结肠炎可能出现的问题之一是对某些食物的饮食过敏。本研究旨在评估溃疡性结肠炎患者中的乳制品过敏情况。本研究是一项病例对照研究，研究了72例溃疡性结肠炎患者，记录疾病史、进行结肠镜检查并经活检确诊，以及72例无结肠炎病史的人。在本研究中，为调查食物过敏，使用了国际代码编号为DP3420 - 1601 - 11E的EUROMMUM试剂盒。我们使用卡方检验和蒙特卡洛方法进行数据分析。在溃疡性结肠炎患者中，30.6%为轻度，52.8%为中度，16.6%为重度。其中9.7%报告有因疾病进行腹部手术的病史。根据卡方检验和蒙特卡洛方法，溃疡性结肠炎组中的乳制品过敏（包括：牛奶、超高温灭菌牛奶和酪蛋白）具有显著性（P = 0.00）。本研究表明，溃疡性结肠炎与牛奶、超高温灭菌牛奶和酪蛋白之间存在显著关系。对乳制品过敏的溃疡性结肠炎患者以及食用乳制品会增加溃疡性结肠炎的严重程度。
