哺乳动物呼吸系统的设计。V. 将形态测量的肺扩散能力按体重比例缩放：野生和家养哺乳动物

Design of the mammalian respiratory system. V. Scaling morphometric pulmonary diffusing capacity to body mass: wild and domestic mammals.

作者信息

Gehr P, Mwangi D K, Ammann A, Maloiy G M, Taylor C R, Weibel E R

出版信息

Respir Physiol. 1981 Apr;44(1):61-86. doi: 10.1016/0034-5687(81)90077-3.

Abstract

This paper utilizes a comparative approach to establish the relationship between morphometric diffusing capacity for oxygen (DLo2) and maximal oxygen consumption (Vo2max). DLo2 and Vo2max were determined on the same 21 individuals in African mammals spanning a range in body mass from 0.4 to 240kg. We confirmed earlier findings that Dlo2 was proportional to Mb0.99 while Vo2max was proportional to Mb0.79. Thus, the ratio of Dlo2/Vo2 is approximately proportional to Mb0.20. We conclude that large animals require a larger pulmonary diffusing capacity to transfer oxygen at the same rate from air to blood.

摘要

本文采用比较方法来建立氧形态计量弥散能力（DLo2）与最大耗氧量（Vo2max）之间的关系。对体重范围从0.4千克到240千克的21只非洲哺乳动物个体同时测定了DLo2和Vo2max。我们证实了早期的研究结果，即DLo2与体重的0.99次方成正比，而Vo2max与体重的0.79次方成正比。因此，DLo2/Vo2的比值大约与体重的0.20次方成正比。我们得出结论，大型动物需要更大的肺弥散能力，以便以相同速率将氧气从空气转移到血液中。