Malchow-Møller A, Matzen P, Bjerregaard B, Hilden J, Holst-Christensen J, Staehr Johansen T, Altman L, Thomsen C, Juhl E
Scand J Gastroenterol. 1981;16(1):1-6.
During approximately 2 years 106 clinical and routine laboratory parameters were obtained from each of 500 jaundiced patients consecutively admitted to the surgical and medical departments in a hospital covering a third of the hospital admissions in the city of Copenhagen. The patients were classified mainly by morphological criteria (397 patients) or the subsequent clinical course (103 patients) into five major diagnostic categories: acute parenchymal jaundice (113 patients), chronic parenchymal jaundice (97 patients), gallstone disease (76 patients), malignant obstructive jaundice (104 patients), and other causes of jaundice (110 patients). The five major categories covered 23 specific diagnoses. Within 3 months of admission 21% of the patients died, and the mortality varied from 4% in acute parenchymal jaundice to 49% in jaundice due to malignant disease.
在大约两年的时间里，从连续入住一家医院外科和内科的500名黄疸患者中，每人获取了106项临床和常规实验室参数。该医院接收的患者占哥本哈根市医院入院患者总数的三分之一。患者主要根据形态学标准（397例患者）或随后的临床病程（103例患者）分为五个主要诊断类别：急性实质性黄疸（113例患者）、慢性实质性黄疸（97例患者）、胆结石病（76例患者）、恶性梗阻性黄疸（104例患者）以及其他黄疸病因（110例患者）。这五个主要类别涵盖了23种具体诊断。入院后3个月内，21%的患者死亡，死亡率从急性实质性黄疸的4%到恶性疾病所致黄疸的49%不等。
