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附睾腺瘤样瘤:其双相性质的超微结构证据。

Adenomatoid tumor of the epididymis: ultrastructural evidence of its biphasic nature.

作者信息

Sidhu G S, Fresko O

出版信息

Ultrastruct Pathol. 1980 Jan-Mar;1(1):39-47. doi: 10.3109/01913128009141393.

DOI:10.3109/01913128009141393
PMID:7233575
Abstract

Two adenomatoid tumors of the epididymis were examined by light and electron microscopy. Epithelial elements were characterized by the presence of a basal lamina investment, gland formation, luminal microvilli, apical junctional complexes, and cytoplasmic tonofibrils. The stomal cells lacked these features and demonstrated marked cytoplasmic elongation, complex cell processes, a more prominent granular endoplasmic reticulum, evidence of phagocytic activity, and an intimate association with the surrounding collagen and elastic fibers. A continuity of cell-to-cell contact between the epithelial and stromal cells was demonstrated along with the presence of cells displaying both epithelial and mesenchymal differentiation. This evidence of the biphasic nature of the neoplasm is consistent with its presumed mesothelial derivation.

摘要

对两个附睾腺瘤样瘤进行了光镜和电镜检查。上皮成分的特征为有基底膜包绕、腺泡形成、腔内微绒毛、顶端连接复合体和细胞质张力丝。间质细胞缺乏这些特征,表现为明显的细胞质伸长、复杂的细胞突起、更显著的粗面内质网、吞噬活性证据以及与周围胶原纤维和弹性纤维的紧密联系。上皮细胞和间质细胞之间显示出细胞间接触的连续性,同时存在表现出上皮和间充质分化的细胞。肿瘤的这种双相性质的证据与其推测的间皮来源一致。

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