Chüden H G
Laryngol Rhinol Otol (Stuttg). 1978 Nov;57(11):997-1007.
An evaluation of Betahistine hydrochloride treatment of 92 patients suffering from Menière disease and Menière-like syndrom is presented. Observed for more than one year 54 (89%) patients showed complete relief of vertigo-attack symptoms. 7 (12%) patients showed a distinct improvement in their hearing as reflected in their audiograms, only 7 (12%) patients showed a further loss of hearing. There appeared to be a trend toward further improvement when therapy was maintained over at least a period of 3--4 month. Vertigo seemed to be the symptom most responsive to treatment and tinnitus the most resistant. Minimal side effects were observed in 17 (18%) patients.
本文介绍了对92例梅尼埃病和梅尼埃样综合征患者进行盐酸倍他司汀治疗的评估。经过一年多的观察，54例（89%）患者的眩晕发作症状完全缓解。7例（12%）患者的听力在听力图上显示有明显改善，只有7例（12%）患者听力进一步下降。当治疗持续至少3至4个月时，似乎有进一步改善的趋势。眩晕似乎是对治疗最敏感的症状，耳鸣则最不敏感。17例（18%）患者观察到轻微副作用。
