de Carvalho A, Graudal H
Acta Radiol Diagn (Stockh). 1980;21(6):797-802. doi: 10.1177/028418518002100617.
A series of 188 patients with rheumatoid arthritis was followed up for 3 to 12 years. An association was found between radiologic progression and limitation of motion for all the joints. Remission of the inflammation occurred more often in the small joints. Early radiologic involvement was most frequent in the upper limb joints and metatarso-phalangeal joints. Clinically, no significant differences existed between upper and lower limbs in the early stages. The single metatarso-phalangeal, metacarpo-phalangeal and proximal interphalangeal joints of the fingers were not more often involved, radiologically or clinically, than many other joints. Four different types of relationship between radiologic progression, on one hand, and articular swelling and tenderness, on the other, were observed.
对188例类风湿性关节炎患者进行了3至12年的随访。发现所有关节的放射学进展与活动受限之间存在关联。炎症缓解在小关节中更常发生。早期放射学受累在上肢关节和跖趾关节中最为常见。临床上，早期上下肢之间没有显著差异。手指的单个跖趾关节、掌指关节和近端指间关节在放射学或临床上并不比许多其他关节更常受累。观察到一方面放射学进展与另一方面关节肿胀和压痛之间存在四种不同类型的关系。
