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经皮胆红素测定法。皮肤黄疸的头-尾进展。

Transcutaneous bilirubinometry. The cephalocaudal progression of dermal icterus.

作者信息

Hegyi T, Hiatt I M, Gertner I, Indyk L

出版信息

Am J Dis Child. 1981 Jun;135(6):547-9.

PMID:7234789
Abstract

The transcutaneous bilirubinometer (TcB) was used to document the cephalocaudal progression of dermal icterus in neonates. The TcB index of a specific area was compared with that of the forehead (TcB ratio). Four surface regions were identified, placed in the following sequence with respect to decreasing TcB ratio values: (1) forehead and sternum; (2) elbow, upper part of the back, and upper part of the abdomen; (3) lower part of the back and knee; and (4) palm and sole. To examine the relationship of the skin region of different serum bilirubin levels, a model was created that allowed the correlation of the TcB index with the specific region's distance from the forehead. Area differences in TcB values at lower bilirubin concentrations were less marked than at high levels. While the mechanism of this phenomenon has not been elucidated, the role of biophysical properties of the skin remains to be explored.

摘要

经皮胆红素仪(TcB)用于记录新生儿皮肤黄疸的头-尾进展情况。将特定区域的TcB指数与前额的TcB指数进行比较(TcB比值)。确定了四个体表区域,按照TcB比值降低的顺序排列如下:(1)前额和胸骨;(2)肘部、背部上部和腹部上部;(3)背部下部和膝盖;(4)手掌和脚底。为了研究不同血清胆红素水平的皮肤区域之间的关系,建立了一个模型,该模型可以将TcB指数与特定区域到前额的距离进行关联。较低胆红素浓度时TcB值的区域差异不如高浓度时明显。虽然这种现象的机制尚未阐明,但皮肤生物物理特性的作用仍有待探索。

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How skin anatomy influences transcutaneous bilirubin determinations: an in vitro evaluation.
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J Clin Monit. 1986 Jan;2(1):53-9. doi: 10.1007/BF01619177.