Das S K, Steen M E, McCullough M S, Bhattacharyya D K
Lipids. 1978 Oct;13(10):679-84. doi: 10.1007/BF02533745.
Lipids from bovine optic nerve were analyzed. The total content of 16.5% by weight included 27.2% nonpolar lipids, 26.1% glycolipids, and 46.7% phospholipids by weight. Free cholesterol was the major component of the nonpolar lipid fraction. The cerebrosides, 73.5% of total glycolipids, were separated by thin layer chromatography (TLC) into two bands (upper and lower) that were present in equal proportion. Cerebroside sulfates comprised about 27.5% of total glycolipids. Gangliosides were also detected in the glycolipid fraction. In order of predominance, choline glycerophospholipids, ethanolamine glycerophospholipids, ethanolamine plasmalogens, serine glycerophospholipids, sphingomyelins, and inositol glycerophospholipids were the major phospholipids. Palmitoyl (16:0), stearoyl (18:0), and oleoyl (18:1) groups were the major acyl groups in all neutral and phospholipid classes. However, ethanolamine glycerophospholipids, serine glycerophospholipids, and inositol glycerophospholipids contained a large percentage of 22:6 (docosahexaenoyl) group. The major alk-1-enyl groups of the plasmalogens were 16:0, 18:0, and 18:1. Steroyl (18:0), lignoceroyl (24:0), and nervonoyl (24:1) were the major acyl groups in all sphingolipids. Lower cerebroside band and cerebroside sulfates contained large amount of hydroxylignoceroyl (cerebronoyl) and hydroxynervonoyl groups.
对牛视神经中的脂质进行了分析。按重量计，总含量为16.5%，其中非极性脂质占27.2%，糖脂占26.1%，磷脂占46.7%。游离胆固醇是非极性脂质部分的主要成分。脑苷脂占总糖脂的73.5%，通过薄层色谱法（TLC）分离为两条带（上带和下带），二者比例相等。硫酸脑苷脂约占总糖脂的27.5%。在糖脂部分也检测到了神经节苷脂。按优势顺序排列，胆碱甘油磷脂、乙醇胺甘油磷脂、乙醇胺缩醛磷脂、丝氨酸甘油磷脂、鞘磷脂和肌醇甘油磷脂是主要的磷脂。棕榈酰基（16:0）、硬脂酰基（18:0）和油酰基（18:1）是所有中性脂质和磷脂类别中的主要酰基。然而，乙醇胺甘油磷脂、丝氨酸甘油磷脂和肌醇甘油磷脂含有很大比例的22:6（二十二碳六烯酰基）基团。缩醛磷脂的主要alk-1-烯基为16:0、18:0和18:1。硬脂酰基（18:0）、木蜡酰基（24:0）和神经酰基（24:1）是所有鞘脂中的主要酰基。较低的脑苷脂带和硫酸脑苷脂含有大量的羟基木蜡酰基（脑酰基）和羟基神经酰基。
