Schmidt W, Klima G
Anat Anz. 1980;148(5):384-91.
A report about a human embryo of about 4 weeks of age afflicted with the formation of amnion cord with a slinglike formation. The corion sac had on its surface only a sparse cover with chorion vili. The intraembryonical vascular system was not shown except of small partial spaces in the front sector. The cause for the formation of an amnion cord is seen primarily in a faulty supply of the amniotic sac with its content. The formation of an amnion cord has been interpreted for this early phase of the embryogenesis as follows: In sufficiency of nourishment led to a dehiscence of the amnion. Mesenchym entered from the extraembryonal celom and combined itself with the lateral wall of embryo which showed because of insufficient nourishment in one area of defective epithelium. The mesenchym, which surrounded the frontal trunk part did not connect with the embryo and grew because of growth pressure into a loop with collagenous fibers. Amnionepithelecells spread only secondarily over the mesenchymloop and epithelialized it.
一份关于约4周龄人类胚胎罹患羊膜索形成且呈吊带样结构的报告。绒毛膜囊表面仅有稀疏的绒毛膜绒毛覆盖。除前部区域有小的局部间隙外,胚胎内血管系统未显示。羊膜索形成的原因主要见于羊膜囊及其内容物供应不足。在胚胎发育的这个早期阶段,羊膜索的形成被解释如下:营养不足导致羊膜裂开。间充质从胚外体腔进入,并与胚胎侧壁结合,由于一个区域上皮营养不足,胚胎侧壁出现缺陷。围绕额部躯干部分的间充质未与胚胎相连,因生长压力而形成带有胶原纤维的环。羊膜上皮细胞只是在间充质环上继发蔓延并使其上皮化。