Bastin R, Rodhain F, Frottier J, Vilde J L, Dournon E, Bricaire F, Charmot G
Ann Med Interne (Paris). 1981;132(2):106-8.
Asiatic dengue was detected in nine tourists. In eight patients it was of the classical benign type, the ninth case being associated with severe thrombopenia (4 000/mm3), but without signs of shock. A brief summary is given of the physiopathology of the hemorrhagic forms of the disease: acquired sensitivity from a primary attack and reinfection with a heterologous virus; selection of virulent strains by an atypical vector; genetic recombination producing a strongly pathogenic virus.
在九名游客中检测出亚洲型登革热。八名患者为典型的良性类型,第九例伴有严重血小板减少症(4000/mm³),但无休克迹象。本文简要概述了该疾病出血型的病理生理学:初次感染和异源病毒再感染后获得的敏感性;非典型媒介对强毒株的选择;产生强致病性病毒的基因重组。