[静脉注射沙丁胺醇后收缩率的多导睡眠图研究]
[Polygraphic study of systolic rates after intravenous administration of salbutamol].
作者信息
Grandillo F, Cacciapuoti F, Rosato G, Giunta R, Spiezia R, Varricchio M
出版信息
Arch Sci Med (Torino). 1980 Jul-Sep;137(3):443-7.
PMID:7235932
Abstract
The effects of salbutamol on the polygraphic pattern were studied in 10 patients with chronic obstructive lung disease. Salbutamol, administered by i.v. injection in a single dose of 100 gamma, caused an increase of heart rate, a decrease of PEP (by decrease in the TCI), a decrease of the Wessler's index and an increase of ejection fraction. These results suggest that salbutamol produces an improvement in cardiac function either by a direct inotropic action or by an afterload decrease.
摘要
对10例慢性阻塞性肺疾病患者研究了沙丁胺醇对多导记录图模式的影响。静脉注射单剂量100微克的沙丁胺醇，可导致心率增加、PEP降低（通过TCI降低）、韦氏指数降低以及射血分数增加。这些结果表明，沙丁胺醇要么通过直接正性肌力作用，要么通过降低后负荷来改善心脏功能。
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