Schirripa V, Attisano N, Sarica G, Grenci G, Martelli G
Minerva Med. 1982 Jan 14;73(1-2):71-5.
10 patients with systemic essential arterial hypertension have been treated with 200 mg/die of Metoprolol. The systolic times have been valued before and after the treatment. It has been observed a reduction of the pre-ejection period simultaneously and proportionally to the reduction of the arterial pressure and the cardiac frequence. These last parameters and the indices of consumption of oxygen and heart frequence have undergone a significant decrease since the first week of therapy. The bloodless indices which express the myocardic contractility demonstrated instead not to be particularly influenced.
10例系统性原发性动脉高血压患者接受了每日200毫克美托洛尔的治疗。在治疗前后对收缩期时间进行了评估。观察到射血前期与动脉压和心率的降低同时且成比例地减少。自治疗第一周起，这些最后的参数以及氧消耗指数和心率均显著下降。相反，反映心肌收缩力的无血指数未受到特别影响。
