Neumann H A, Berretty P J, Folmer S C, Cormane R H
Br J Dermatol. 1981 Apr;104(4):383-8. doi: 10.1111/j.1365-2133.1981.tb15307.x.
Urticaria is known to occur in the pre-icteric phase of acute viral hepatitis. Often such urticaria is a symptom of a serum sickness-like syndrome which can be a prodrome of viral hepatis. Immune complexes are thought to be pathogenetic in this condition. In this paper we present two patients with a serum sickness-like syndrome, urticaria and hepatitis B. By immunofluorescence techniques Hepatitis B surface antigen, CIq and C3 could be demonstrated in the blood vessels of the superficial dermis. These findings are consistent with the immune complex hypothesis.
已知荨麻疹可发生于急性病毒性肝炎的黄疸前期。通常这种荨麻疹是血清病样综合征的一种症状，而血清病样综合征可能是病毒性肝炎的前驱症状。免疫复合物被认为在这种情况下具有致病作用。在本文中，我们报告了两名患有血清病样综合征、荨麻疹和乙型肝炎的患者。通过免疫荧光技术，在浅表真皮的血管中可检测到乙型肝炎表面抗原、补体C1q和C3。这些发现与免疫复合物假说相符。
