8-甲氧补骨脂素诱导哺乳动物表皮晒伤细胞的作用光谱。
An action spectrum for 8-MOP induced sunburn cells in mammalian epidermis.
作者信息
Young A R, Magnus I A
出版信息
Br J Dermatol. 1981 May;104(5):541-8. doi: 10.1111/j.1365-2133.1981.tb08168.x.
The histological change known as individual cell shrinkage necrosis (so-called "sunburn cell' in mammalian epidermis) would seem to be suitable for quantitative morphological studies on the effect of psoralen treatment and near UV irradiation. The number of sunburn cells per unit length of epidermis versus varying doses of narrow waveband UVR, 305-375 nm, has been studied and an action spectrum constructed which has maximal activity at 320-335 nm. The implications of these findings are discussed.
被称为单个细胞皱缩坏死的组织学变化（在哺乳动物表皮中即所谓的“晒伤细胞”）似乎适用于对补骨脂素治疗和近紫外线照射效果的定量形态学研究。研究了表皮单位长度上晒伤细胞的数量与不同剂量的窄波段紫外线辐射（305 - 375纳米）的关系，并构建了一个作用光谱，该光谱在320 - 335纳米处具有最大活性。讨论了这些发现的意义。
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