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地塞米松处理的小鼠心肌脂质小滴的积累。

Accumulation of myocardial lipid droplets in dexamethasone-treated mice.

作者信息

Lie R K, Jodalen H G, Rotevatn S

出版信息

Cell Tissue Res. 1981;216(3):661-3. doi: 10.1007/BF00238661.

DOI:10.1007/BF00238661
PMID:7237524
Abstract

Conventionally fixed and plastic-embedded myocardial tissue from mice treated with 1 mg/kg body weight dexamethasone for 48 h was examined in the electron microscope. The dexamethasone-treated mice showed a marked increase in the accumulation of lipid droplets, as compared with control animals. The percent volume of lipid droplets, calculated by morphometric analysis, showed a significant increase in the dexamethasone-treated mice. No other ultrastructural difference between dexamethasone-treated mice and controls was observed.

摘要

对用1毫克/千克体重地塞米松处理48小时的小鼠的传统固定和塑料包埋心肌组织进行电子显微镜检查。与对照动物相比,用地塞米松处理的小鼠脂滴积累明显增加。通过形态计量分析计算的脂滴体积百分比显示,用地塞米松处理的小鼠有显著增加。未观察到用地塞米松处理的小鼠与对照之间的其他超微结构差异。

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引用本文的文献

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The 'borderzone zone' controversy. A study of theory structure in biomedicine.
Theor Med. 1986 Oct;7(3):243-58. doi: 10.1007/BF00539846.
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Myocardial diseases of animals.动物的心肌疾病
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本文引用的文献

1
AN ELECTRON MICROSCOPIC STUDY OF CARDIAC NECROSIS PRODUCED BY 9 ALPHA-FLUOROCORTISOL AND SODIUM PHOSPHATE.9α-氟皮质醇与磷酸钠所致心脏坏死的电子显微镜研究
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HISTOLOGICAL AND HISTOCHEMICAL CHANGES IN THE MUSCLES OF RABBITS GIVEN THE CORTICOSTEROID TRIAMCINOLONE.给予皮质类固醇曲安西龙的兔子肌肉的组织学和组织化学变化
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The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.在电子显微镜检查中,将高pH值的柠檬酸铅用作电子不透明染色剂。
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Steroid myopathy. Report of five cases occurring during treatment of rheumatic fever.类固醇肌病。风湿热治疗期间发生的5例报告。
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Pathogenesis of "electrolyte-steroid-cardiopathy".“电解质-类固醇心肌病”的发病机制
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6
Necrosis and regeneration of skeletal muscles in cortisone-treated rabbits.可的松治疗的兔子骨骼肌的坏死与再生
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The effects of glucocorticoids on red and white muscles in the rat.糖皮质激素对大鼠红白肌的影响。
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Electron microscopic observations in thyrotoxic and corticosteroid-induced myopathies.
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Electron microscopic study of myocardial changes produced in rats by the concurrent administration of 9-alpha-fluorocortisol, Na2HPO4 and corn oil.对同时给予9-α-氟皮质醇、磷酸氢二钠和玉米油的大鼠所产生的心肌变化进行的电子显微镜研究。
Cardiologia (Basel). 1969;54(1):16-29. doi: 10.1159/000166239.
10
Effect of free fatty acids on myocardial function and oxygen consumption in intact dogs.游离脂肪酸对完整犬心肌功能和氧消耗的影响。
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