Lie R K, Jodalen H G, Rotevatn S
Cell Tissue Res. 1981;216(3):661-3. doi: 10.1007/BF00238661.
Conventionally fixed and plastic-embedded myocardial tissue from mice treated with 1 mg/kg body weight dexamethasone for 48 h was examined in the electron microscope. The dexamethasone-treated mice showed a marked increase in the accumulation of lipid droplets, as compared with control animals. The percent volume of lipid droplets, calculated by morphometric analysis, showed a significant increase in the dexamethasone-treated mice. No other ultrastructural difference between dexamethasone-treated mice and controls was observed.
对用1毫克/千克体重地塞米松处理48小时的小鼠的传统固定和塑料包埋心肌组织进行电子显微镜检查。与对照动物相比,用地塞米松处理的小鼠脂滴积累明显增加。通过形态计量分析计算的脂滴体积百分比显示,用地塞米松处理的小鼠有显著增加。未观察到用地塞米松处理的小鼠与对照之间的其他超微结构差异。