一些新型99mTc标记的乙酰苯胺基亚氨基二乙酸酯的体内比较动力学
Comparative in vivo kinetics of some new 99mTc-labelled acetanilido iminodiacetates.
作者信息
Chiotellis E, Varvarigou A, Koutoulidis C
出版信息
Eur J Nucl Med. 1981;6(6):241-4. doi: 10.1007/BF00251345.
PMID:7238541
Abstract
The in vivo kinetics of five new 99mTc-labelled acetanilido iminodiacetates, analogous to 99mTc-p-butyl IDA, were studied in experimental animals by means of their distribution in mice and scintigrams of rabbits. The new compounds were specifically eliminated via the hepatobiliary system with various rates of hepatic extraction. Urinary excretion of the complexes was minimal.
摘要
通过在小鼠体内的分布以及兔的闪烁扫描图，对五种类似于99mTc-p-丁基IDA的新型99mTc标记乙酰苯胺基亚氨基二乙酸酯在实验动物体内的动力学进行了研究。新化合物通过肝胆系统以不同的肝脏摄取率被特异性清除。复合物的尿液排泄极少。
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