von Cramon D, Kühnlein J, Wolfram A
Fortschr Neurol Psychiatr. 1981 Apr;49(4):129-35.
The CAT-scan permits the localization of small thalamic lesions. Based on such findings various clinical syndromes can be evaluated which before the era of computertomography could be diagnosed by histological examination of the brain only. It is well known that the bilateral destruction of certain thalamic nuclei leads to a dementia which Grünthal (1942) accordingly coined thalamic dementia. The features of this syndrome of dementia have been discussed in detail; as to the clinical picture, the striking correspondence with bifrontal syndromes has been emphasized. It has been stressed that despite a decline of social intelligence the formal intelligence, as measured by standard tests, may be preserved, a fact likewise comparable with frontal syndromes. Finally, the question has been discussed how to delineate the amnesic thalamic syndrome and the syndrome of thalamic dementia.
计算机断层扫描（CAT扫描）能够定位丘脑小病灶。基于这些发现，可以评估各种临床综合征，而在计算机断层扫描时代之前，这些综合征只能通过大脑组织学检查来诊断。众所周知，某些丘脑核团的双侧破坏会导致痴呆，因此格伦塔尔（1942年）将其命名为丘脑性痴呆。这种痴呆综合征的特征已被详细讨论；就临床表现而言，人们强调了它与双侧额叶综合征的显著相似之处。有人强调，尽管社交智力有所下降，但通过标准测试测量的形式智力可能得以保留，这一事实同样与额叶综合征相似。最后，人们讨论了如何区分遗忘性丘脑综合征和丘脑性痴呆综合征。
