Chicarilli Z N
Ann Plast Surg. 1987 Mar;18(3):230-7. doi: 10.1097/00000637-198703000-00009.
The pathophysiology and treatment of hidradenitis suppurativa, acne conglobata, and dissecting cellulitis of the scalp, which constitute the follicular occlusion triad, are reviewed. The unusual occurrence of all three components in a single patient resistant to medical management is presented with a review of the literature. This patient's course was complicated by multiple synchronous squamous cell carcinomas developing in a localized area where his acne conglobata was most pronounced. Although one lesion was clinically obvious, the majority were less suspicious for cancer. Occult cancer should be considered in recalcitrant cases of acne conglobata where isolated areas fail to respond to medical management, particularly when 13-cis-retinoic acid has been used.
本文综述了构成毛囊闭锁三联征的化脓性汗腺炎、聚合性痤疮和头皮穿掘性蜂窝织炎的病理生理学及治疗方法。文中介绍了一名对药物治疗耐药的患者同时出现这三种病症的罕见病例，并回顾了相关文献。该患者的病程因在聚合性痤疮最明显的局部区域出现多个同步发生的鳞状细胞癌而变得复杂。尽管有一个病灶在临床上很明显，但大多数病灶的癌症嫌疑较小。对于聚合性痤疮的顽固病例，尤其是在使用13 - 顺式维甲酸治疗后，孤立区域对药物治疗无反应时，应考虑隐匿性癌症的可能。
