阿根廷慢性肝炎中的乙肝病毒和甲肝病毒感染

HBV and HAV infection in chronic hepatitis in Argentina.

作者信息

Tanno H, Fay O H, Roncoroni M, Palazzi J

出版信息

J Med Virol. 1981;7(1):61-5. doi: 10.1002/jmv.1890070107.

Abstract

Sera of 155 chronic hepatitis (CH) patients in Argentina were tested for the presence of HBsAg, anti-HBs, anti-HBc, and anti-HAV. Our purpose was to define the role that both virus A and B might play in the etiology and pathogenesis of this condition. The patients were divided into two groups: group I (57) HBsAg-negative; group II (98) HBsAg-positive. The control group consisted of 1,209 healthy blood donors from Banco Central de Sangre de Rosario; 286/1,209 (24%) had viral markers for HBV. In group I, 38/57 (67%) had anti-HBs and/or anti-HBc, but none had anti-HBs alone. Group II showed a higher percentage of males (P less than 0.05). We found similar incidence of anti-HAV among group I, group II, and the control group.

摘要

对阿根廷155例慢性肝炎（CH）患者的血清进行了乙肝表面抗原（HBsAg）、乙肝表面抗体（抗-HBs）、乙肝核心抗体（抗-HBc）和甲型肝炎抗体（抗-HAV）检测。我们的目的是确定甲型和乙型病毒在这种疾病的病因和发病机制中可能发挥的作用。患者分为两组：第一组（57例）HBsAg阴性；第二组（98例）HBsAg阳性。对照组由来自罗萨里奥中央血库的1209名健康献血者组成；1209人中286人（24%）有乙肝病毒标志物。在第一组中，38/57（67%）有抗-HBs和/或抗-HBc，但无人仅有抗-HBs。第二组男性比例较高（P<0.05）。我们发现第一组、第二组和对照组中抗-HAV的发生率相似。