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Pharmacokinetic investigations of Craviten. IV. First-pass metabolism in rats.

作者信息

Danek A, Witek J

出版信息

Pol J Pharmacol Pharm. 1980 Nov-Dec;32(6):949-53.

PMID:7243692
Abstract

Pharmacokinetic analysis of serum levels of Craviten found after oral and iv injection suggests, that the examined drug has a relatively low systemic availability. This lack of availability may be attributed to the metabolism of Craviten during the first passage into the circulation after oral administration.

摘要

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