Biagi P
Quad Sclavo Diagn. 1980 Jun;16(2):206-13.
Plasma disappearance rate of sulfobromophthalein (BSF), a second stage diagnostic methodology for hepatic illness, has been widely used in testing functional derangement of chronic alcoholic liver disease. However kinetics parameters show wide range of values so it is difficult, in the single patient, to make a reliable differential diagnosis between chronic alcoholic hepatitis and cirrhosis, by this mean. The Author using BSF kinetics parameters calculated a discriminatory function which allows to assess the nosography of alcoholic hepatic affection with a low grade of mistake in the single patient; the suppose that this function improve the sensitivity of BSF plasma disappearance rate and make this second stage procedure more useful in testing chronic alcoholic liver diseases.
磺溴酞钠(BSF)的血浆消失率作为肝病的第二阶段诊断方法,已广泛用于检测慢性酒精性肝病的功能紊乱。然而,动力学参数显示出广泛的值范围,因此,通过这种方法,在单个患者中很难对慢性酒精性肝炎和肝硬化进行可靠的鉴别诊断。作者利用BSF动力学参数计算出一种判别函数,该函数能够在单个患者中以较低的错误率评估酒精性肝损伤的病情分类;推测该函数提高了BSF血浆消失率的敏感性,并使这一第二阶段程序在检测慢性酒精性肝病中更有用。