Miwa M, Kikuchi K, Senoue I, Watanabe H, Nomiyama T, Suzuki S, Harasawa S, Tani N, Miwa T
Tokai J Exp Clin Med. 1980 Oct;5(4):451-6.
Differences in distribution of age, hemoglobin values, location and number of ulcers, activities of gastric secretion, associated conditions, treatment and prognoses between bleeding and non-bleeding gastric ulcer patients were studied. The ages of bleeding patients were distributed more widely than those of non-bleeding patients and the number of patients over 70 years of age was greater in bleeding patients than in non-bleeding patients. Associated conditions of bleeding patients were more serious than those of non-bleeding patients and some bleeding patients showed coagulation disorders. Fifteen out of 17 bleeding patients were treated and well controlled surgically, and seven out of 62 bleeding patients who were treated medically died. In this study, the exact cause which made the difference between bleeding ulcers and non-bleeding ulcers could not be found. Bleeding ulcer patients with associated conditions did not always die directly from bleeding, but the bleeding decreased their general condition and, as a result, they died. Therefore, surgical treatment is the first choice in these patients if their conditions will tolerate such treatment.
研究了出血性和非出血性胃溃疡患者在年龄分布、血红蛋白值、溃疡位置和数量、胃分泌活动、相关病症、治疗及预后等方面的差异。出血患者的年龄分布比非出血患者更广泛,70岁以上出血患者的数量多于非出血患者。出血患者的相关病症比非出血患者更严重,部分出血患者出现凝血障碍。17例出血患者中有15例接受了手术治疗且病情得到良好控制,62例接受药物治疗的出血患者中有7例死亡。在本研究中,未能找到导致出血性溃疡和非出血性溃疡出现差异的确切原因。伴有相关病症的出血性溃疡患者并非总是直接死于出血,而是出血使他们的全身状况恶化,最终导致死亡。因此,如果患者病情能够耐受手术治疗,手术治疗是这些患者的首选。