Borzemska M
Polim Med. 1978;8(2):57-64.
The examination of haemolytic activity of aqueous plastic extracts represents one of the method to evaluate plastics of medical grade. In own examinations different methods were used to estimate the haemolytic activity of aqueous extracts of some toxic materials, e.g. technical gums, epoxides, also silicone resins, which are admitted to medical use. On the basis of literature and own examinations the most sensitive method to estimate the haemolytic test was found to be the method after the Japanese Pharmacopoeia. The degree of haemolysis due to the water extracts both of technical gums and epoxides was found to be significantly different from the norms. The silicone resins fulfilled the demands for medical materials. On the basis of the results, the method described in the Japanese Pharmacopoeia was accepted as an appropriate test for evaluation of haemolytic activity of aqueous plastic extracts designed to blood contact or to implantation.
水性塑料提取物溶血活性的检测是评估医用级塑料的方法之一。在我们自己的检测中，使用了不同的方法来评估一些有毒材料（如工业用胶、环氧化合物以及获准用于医疗用途的硅树脂）的水性提取物的溶血活性。基于文献和我们自己的检测，发现评估溶血试验最灵敏的方法是日本药典中的方法。结果发现，工业用胶和环氧化合物的水提取物引起的溶血程度与标准有显著差异。硅树脂符合医用材料的要求。基于这些结果，日本药典中描述的方法被认可为评估用于血液接触或植入的水性塑料提取物溶血活性的合适检测方法。
