Stenhammar L, Johansson C G
Acta Paediatr Scand. 1981;70(3):379-81. doi: 10.1111/j.1651-2227.1981.tb16567.x.
Among children born between 1969 and 1977 in two areas of south-east Sweden an initial flat small intestinal mucosa was found in 84 cases, 64 of whom were considered to have coeliac disease (CD) diagnosed mostly according to the criteria formulated by the European Society for Paediatric Gastroenterology and Nutrition. The incidence of CD was 1/859, which is in agreement with that of a recent report from south Sweden. This suggests that the incidence of CD is the same in the whole of Sweden. In the present study all patients with an initial flat mucosa improved clinically and histologically after 1 year or more on a gluten-free diet. When challenged with gluten, 19% did not relapse within 2 years, thus fulfilling the criteria for so-called transient gluten intolerance. These patients had a lower mean age of symptom debut and for first biopsy, compared with the patients with CD.
在瑞典东南部两个地区1969年至1977年出生的儿童中，发现84例初始小肠黏膜扁平，其中64例被认为患有乳糜泻（CD），大多根据欧洲儿科胃肠病学和营养学会制定的标准进行诊断。CD的发病率为1/859，这与瑞典南部最近的一份报告一致。这表明瑞典全国CD的发病率相同。在本研究中，所有初始黏膜扁平的患者在采用无麸质饮食1年或更长时间后，临床和组织学上均有改善。当再次接触麸质时，19%的患者在2年内未复发，从而符合所谓的短暂性麸质不耐受标准。与CD患者相比，这些患者出现症状首发和首次活检时的平均年龄较低。
