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大鼠外侧巨细胞旁核。形态与细胞学

The nucleus paragigantocellularis lateralis in the rat. Conformation and cytology.

作者信息

Andrezik J A, Chan-Palay V, Palay S L

出版信息

Anat Embryol (Berl). 1981;161(4):355-71. doi: 10.1007/BF00316048.

DOI:10.1007/BF00316048
PMID:7247034
Abstract

The nucleus paragigantocellularis lateralis (PGCL) is located in the ventral portion of the rostral medulla. Serial sections of the rat brainstem were examined in the three cardinal planes and the boundaries of the PGCL were determined. In order to visualize the shape and extent of the nucleus, a three-dimensional reconstruction of the PGCL was made from a series of coronal sections. Measurements of neuronal areas, lengths, and widths indicate that a number of neuronal types are present. Small neurons measure less than 150 micron2 and large neurons greater than 250 micron2. Some neuronal types are distributed preferentially throughout the PGCL, and on this basis the nucleus may be divided into caudal and rostral subgroups. Most large neurons (greater than 250 micron2) are found in the caudal portion. Certain neurons contain intranuclear rods, and these neurons are often disposed in small groups, especially common the caudal PGCL. Two morphologically distinct neuronal types incorporate 3H-serotonin when this marker is infused into the ventricular system; the other neurons not marked by this method probably contain other, different transmitters. On the basis of neuronal measurements and staining qualities, it is ascertained that the PGCL is a parvocellular reticular nucleus characterized by many neuronal types.

摘要

外侧巨细胞旁核(PGCL)位于延髓前部的腹侧。在大鼠脑干的三个主要平面上检查了连续切片,并确定了PGCL的边界。为了观察该核的形状和范围,从一系列冠状切片制作了PGCL的三维重建。神经元面积、长度和宽度的测量表明存在多种神经元类型。小神经元面积小于150平方微米,大神经元面积大于250平方微米。一些神经元类型优先分布于整个PGCL,据此该核可分为尾侧和吻侧亚组。大多数大神经元(大于250平方微米)见于尾侧部分。某些神经元含有核内杆状物,这些神经元常成群分布,在尾侧PGCL尤为常见。当将这种标记物注入脑室系统时,两种形态学上不同的神经元类型摄取3H-5-羟色胺;未被该方法标记的其他神经元可能含有其他不同的神经递质。根据神经元测量和染色特性,确定PGCL是一个以多种神经元类型为特征的小细胞网状核。

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