萘替芬的体内抗真菌活性。
In vivo antimycotic activity of naftifine.
作者信息
Petranyi G, Georgopoulos A, Mieth H
出版信息
Antimicrob Agents Chemother. 1981 Mar;19(3):390-2. doi: 10.1128/AAC.19.3.390.
Abstract
Naftifine, a new antifungal agent belonging chemically to the allylamines, was tested for its in vivo activity after topical application against guinea pig skin infections caused by Trichophyton mentagrophytes, T. mentagrophytes var. quinckeanum, or Microsporum racemosum. Compared with standard compounds, naftifine proved to be highly effective mycologically and clinically after topical application in the above models.
摘要
萘替芬是一种化学上属于烯丙胺类的新型抗真菌剂，经局部应用后，对豚鼠由须癣毛癣菌、须癣毛癣菌昆克变种或总状小孢子菌引起的皮肤感染进行了体内活性测试。与标准化合物相比，在上述模型中局部应用后，萘替芬在真菌学和临床上均被证明具有高效性。
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